Clinical Study "Common" Name (formal title) Number of enrollees Funding source (pharma/NIH) Year complete Primary publication Full study treatment protocol
BALATON
[A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion]

COMINO
[A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion]
Total:
BALATON - BRVO:
N = 553

COMINO - CRVO:
N = 729
Genentech/Hoffman-La Roche

BALATON: NCT04740905

COMINO: NCT04740931
BALATON
Primary completion: July 2022
Study completion: June 2023

COMINO
Primary completion: August 2022
Study completion: July 2023
Tadayoni R, Paris LP, Danzig CJ, et al. Efficacy and safety of faricimab for macular edema due to retinal vein occlusion: 24-week results from the BALATON and COMINO trials. Ophthalmology. Published online January 25, 2024. doi.org/10.1016/j.ophtha.2024.01.029 (Pg 4)
[Khanani.Macula Society.2023]