Clinical Study "Common" Name (formal title) Number of enrollees Funding source (pharma/NIH) Year complete Primary publication Full study treatment protocol
GATHER1
[A Phase 2/3 Randomized, Double-Masked, Controlled Trial to Assess the Safety and Efficacy of Intravitreous Administration of Zimura™ (Anti-C5 Aptamer) in Subjects With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration]
Total: 286 Iveric Bio
NCT02686658
Primary completion: September 2019
Study completion:
April 2020
Jaffe GJ, Westby K, Csaky KG, et al. C5 inhibitor avacincaptad pegol for geographic atrophy due to age-related macular degeneration: A randomized pivotal phase 2/3 trial. Ophthalmology. 2021;128:576-586. doi.org/10.1016/j.ophtha.2020.08.027
Jaffe_Fig 1