Clinical Study "Common" Name (formal title) | Number of enrollees | Funding source (pharma/NIH) | Year complete | Primary publication | Full study treatment protocol |
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[Faricimab versus the standard of care for neovascular age-related macular degeneration in Italy: an indirect treatment comparison] | n = 776 | Hoffman LaRoche | 2024 | Galeone C, Turati F, Nicolò M, et al. Faricimab versus the standard of care for neovascular age-related macular degeneration in Italy: an indirect treatment comparison. Drug Target Insights. 2024;18(1):105-111. |
Individual patient-level data from the phase III clinical trials TENAYA and LUCERNE (faricimab cohort) and the real-world study RADIANCE (RADIANCE cohort) were used. An indirect comparison of the efficacy at 1 year of faricimab in two phase III clinical trials and the corresponding effectiveness of anti-VEGF in a real-world study was performed on patients with nAMD matched through propensity score weighting. |